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Factors associated with healthy aging

Factors associated with healthy aging - https://www.nature.com/articles/s41591-023-02495-1

Latin American populations may present heterogeneous patterns of demographic,  socioeconomic, ethnic, and cultural diversity that can defy current universal models of healthy aging. The potential heterogeneous combination of factors that shape aging across underserved populations in Latin American countries (LACs) remains unknown. Compared to other regions where classical factors such as age and sex drive healthy aging, higher disparity-related predictors and between-country variability could influence healthy aging in LACs. We investigated the combined impact of social determinants of health (SDH), health conditions (cardiometabolic risks), lifestyle factors, mental health conditions, and demographics (age, sex) on healthy aging across LACs with different socioeconomic levels. Cross-sectional (N=31,680) and longitudinal (N=9,258) machine-learning models identified the main predictors of cognition and functional ability. Predictors associated with social and health disparities, including SDH, mental health conditions, and cardiometabolic risks, significantly influenced healthy aging more than age and sex. These heterogeneous patterns were more pronounced in low-middle- and upper-middle-income countries compared to high-income countries and a non-Latin American country (for additional longitudinal comparison). Inter-country heterogeneity was considerable. Results do not support current one-size-fits-all approaches to global aging. These inequity-associated and region-specific patterns suggest tailored public health interventions and regional risk assessments of healthy aging in Latin America.

Buscador UdeSA

Heterogeneous risk factors impact aging in Latin American populations

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UdeSA - Universidad de San Andrés

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