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From clinical profiling to differential diagnosis

From clinical profiling to differential diagnosis - https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.15766

In this issue of European Journal of Neurology, Robinson et al. present a novel study on primary progressive apraxia of speech. The authors describe different clinicopathological profiles in patients with left-dominant, right-dominant, and bilateral atrophy of the sup- plementary motor area and lateral premotor cortex. This commentary discusses the im- portance of this evidence for understanding individual differences among these patients, distinguishing them from those with nonfluent variant primary progressive aphasia, and analyzing the relations between motor speech deficits and underlying pathology.

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Patterns of hemispheric compromise in primary progressive apraxia of speech: From clinical profiling to differential diagnosis

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